Set in the mid-1800s Qing Dynasty, Curse of the Royal Harem is loosely based on the reign of the Daoguang Emperor of China and tells of the drama and romantic intrigue in the court’s Manchurian royal harem. At the same time Emperor Daoguang (Sunny Chan) announced that Tunggiya Yuen Yuen (Myolie Wu) will become the Empress Consort Hao Sun, Empress Dowager Kung Chee (Gigi Wong) forced her elder son’s wife, Niuhuru Yee Lan (Jessica Hsuan) to be a sacrificial victim at the prince’s funeral. Emperor Daoguang put aside the ceremony in which Yuen Yuen would be pronounced the Empress Consort in order to save childhood friend, Yee Lan. Emperor Daoguang broke tradition and declared Yee Lan his concubine, inciting a jealous rivalry among concubines in the palace. Left exhausted by the repeated battles, Emperor Daoguang also accidentally discovered that Empress Consort Hao Sun was allegedly having an affair with his younger half-brother, Prince Sui (Joel Chan). Caught between the different political forces within the palace, Yee Lan did not want her fate to be maneuvered by others. Abandoning her kind nature and turning evil instead, Yee Lan became a ruthless woman.